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Dr. Chang's interests include aging, pain, palliative and end-of-life care research, Patient-Reported Outcomes (PRO), health communications, health literacy, health services research, medical informatics, clinical infometrics, psychometrics, Health-Related Quality of Life (HRQOL), caregiver health, clinical decision making, Item Response Theory (IRT), Rasch Measurement Models, Item Banking and Computerized Adaptive Testing (CAT).